The Englander Institute for Precision Medicine and the Department of Pathology and Laboratory Medicine at Weill Cornell Medicine offer a two-year Research Pathology Fellowship in Precision Medicine. With a major exposure to oncologic pathology and a comprehensive translational research component, this training program will focus on the application of next-generation sequencing platforms to identify and validate novel alterations in an array of tumor types.
Objectives: The goal of this Research Pathology Fellowship program is to gain expertise in the application of state-of-the-art sequencing technologies, familiarize with novel tools to analyze next-generation sequencing data, and to become leaders in the field of Precision Medicine. The Research Pathology Fellow will act as a bridge between pathologists, oncologists, surgeons, computational biologists and basic scientists, in order to use next-generation sequencing of tumor genomes and pre-clinical models in high impact research studies.
Responsibilities and learning opportunities:
- To familiarize with operation of latest next-generation sequencing technologies including whole-genome sequencing and spatial omics platforms.
- To learn about the data processing pipeline and bioinformatics aspects of next-generation sequencing.
- To be involved in the development and validation of research assays.
- To participate in research pathology-related activities of next-generation biobanking including our pan-cancer Rapid Autopsy program.
- To develop skills in sequencing data interpretation with computational scientists and bioinformaticians.
- To present de-identified clinico-pathologic and next-generation sequencing results at the CME-accredited Precision Medicine Research Conference.
Requirements: Candidates who have completed pathology residency and pathologists in training will be considered. Prior experience in molecular biology/molecular pathology and/or prior fellowship training is encouraged.
Number of Appointments: One position is available to start around March 1, 2024.
Facilities: The Englander Institute for Precision Medicine at Weill Cornell Medicine is a translational research hub to promote molecular diagnostics and therapeutics. Physician-scientists at the Institute utilize research next-generation sequencing platforms and novel computational algorithms to identify the genetic influencers of a patient’s cancer and use this genetic information to design more effective projects and potential translation into translational research studies. Patients with advanced or refractory cancer consent to our IRB-approved Precision Medicine study. Through an integrative sequencing strategy, potentially relevant targets are identified and reviewed at the CME-accredited multi-disciplinary Precision Medicine Research Conference, with experts from medical oncology, pathology, computational biology, genetics, and ethics. The Institute’s main research resources are next-generation genomics, pathology, biobanking and computational biology, all of which facilitate the most efficient coupling of potentially new, biologically relevant targets to the right cancer patients.
Faculty: Juan Miguel Mosquera, MD, Olivier Elemento, PhD, Cora N. Sternberg, MD, Andrea Sboner, PhD.
Community: The Institute is located in a beautiful residential neighborhood along the East River in Manhattan within walking distance of Central Park and the midtown entertainment and shopping areas. Attractions include major museums, concert halls, theaters, and an opera house all of which are in close proximity.
Stipends: Salaries are commensurate with the level of training.
Applications: Please send Curriculum vitae, personal statement and two letters of recommendation to: