Dear Members of the Englander Institute,
We are thrilled to announce that applications are now being accepted for our very popular 6-week Summer Program for high school, college, and grad students, hosted by the EIPM and the Meyer Cancer Center! Students will actively participate in a range of projects related to cancer biology, precision medicine, cancer epidemiology, health disparities, academic research, computational biomedicine, journal clubs, professional development courses and more.
Registration also just opened for the 2023 Health Hackthon, presented by Entrepreneurship at Cornell and WCM’s Clinical & Translational Science Center! The 9th annual weekend event brings together teams comprised of medical, business, engineering, and design students from Cornell in Ithaca, Cornell Tech, the EIPM, CTSC and beyond create solutions to human health & wellness challenges. Please join me in encouraging our students to register and compete for bragging rights and the chance to win $5,000!
Thank you again for your hard work and dedication to our mission.
Sincerely,
Olivier Elemento, Ph.D.
News Coverage & Awards
Congratulations to our Director for Liquid Biopsy Research Dr. Pashtoon Kasi (left) and Dr. Scott T. Tagawa on accruing the most WCM patients to therapeutic & non-therapeutic studies in Dec. 2022!
=Clinical Director Dr. Cora N. Sternberg was interviewed for the article “Treatment Options for Metastatic Hormone-Sensitive Prostate Cancer, Advances and Barriers,” which appeared in UroToday on January 23rd. Dr. Sternberg also discussed “Combination of Niraparib and Abiraterone Acetate Plus Prednisone Radiographic PFS as a First-Line Therapy in Patients with HRR Gene-Mutated mCRPC, MAGNITUDE,” with UroToday on January 18th.
Dr. Bishoy Faltas provided the Expert Commentary, “Avelumab and Talazoparib Treatment in Patients with Advanced Urothelial Cancer,” to UroToday on January 11th; and “Neoadjuvant Gemcitabine-Carboplatin Versus Gemcitabine-Cisplatin in Patients with Muscle-Invasive Bladder Cancer,” in UroToday on January 19th.
Dr. Peter Martin was interviewed for the recap article “Breakthroughs in Mantle Cell Lymphoma From ASH 2022,” that appeared in MedScape on January 4th.
Events
Our colleague Dr. Daniela Guevara presented an EIPM Precision Medicine Conference lecture, “Unusual Presentation of Advanced Urothelial Cancer in a Young Patient,” on January 26th.
On January 26th Dr. Melissa B. Davis presented her latest work in collaboration with the EIPM, New York Genome Center, WCM’s Meyer Cancer Center and Pathology and Laboratory Medicine departments from her new role with the Morehouse School of Medicine.
Dr. Karsten Suhre presented a WCM Research Cores Seminar, “Discovery of COVID-Associated Proteins in a Joint WCM-NY and Qatar Collaboration Using the OLINK platform,” on January 23rd. Dr. Suhre also organized a WCM-Qatar Weekly Research Seminar, “Non-invasive Methods for Kidney Rejection Prognosis,” on January 15th.
Our Director for Liquid Biopsy Research Dr. Pashtoon Kasi participated in a number of events at ASCO’s recent Gastrointestinal Cancers Symposium, including taking over their OncLive Twitter account on January 21st! Dr. Kasi also participated in the ASCO Daily News article “Real-World Analysis Shows Utility of ctDNA Kinetics in Patients With Advanced Colorectal Cancer,” published on January 17th. Finally, Dr. Kasi was also interviewed for the article, “Expert Details ‘Striking’ Data When Using ctDNA to Predict Early Response in CRC,” in Cancer Network on January 27th.
Our Scientific Director Dr. Massimo Cristofanilli presented “Molecular Heterogeneity and Evolution of Luminal Breast Cancer: Clinical and Therapeutic Challenges,” during a Meyer Cancer Center Experimental Therapeutics Research Program Meeting on January 20th.
Publications
“Tumor-intrinsic IRE1α signaling controls protective immunity in lung cancer,” by Dr. Vivek Mittal, Professor of Cardiothoracic Surgery and an EIPM Member, with our colleagues Drs. Bhavneet Bhinder, Akanksha Verma, Nasser Altorki and myself in Nature Communications on January 9th.
“Population-Level Prevalence of Rare Variants Associated With Atrial Fibrillation and its Impact on Patient Outcomes,” by Dr. Scott Kulm, myself and WCM colleagues in Clinical Electrophysiology on January 18th.
Clinical Director Dr. Cora N. Sternberg published several papers in January including, “Safety Profile of Ipatasertib Plus Abiraterone vs Placebo Plus Abiraterone in Metastatic Castration-resistant Prostate Cancer,” in Clinical Genitourinary Cancer on January 7th; coauthored “New prognostic model in patients with advanced urothelial carcinoma treated with second-line immune checkpoint inhibitors,” in the Journal for ImmunoTherapy of Cancer on January 10th; and coauthored “Differential responses to taxanes and PARP inhibitors in ATM- versus BRCA2-mutated metastatic castrate-resistant prostate cancer,” in the February 15th edition of The Prostate.
“An atlas of substrate specificities for the human serine/threonine kinome,” by our colleague Dr. Lewis C. Cantley, with coauthors Drs. Tomer M. Yaron, Alexander Kerelsky, and myself, in Nature on January 11th.
“Facts and Perspectives: Implications of tumor glycolysis on immunotherapy response in triple negative breast cancer,” by EIPM members Drs. Kristy A. Brown and Eleni Andreopoulou, with WCM colleagues including Dr. Sandra Demaria from Pathology and Laboratory Medicine, in Frontiers in Oncology on January 10th.
“Cell-of-Origin Targeted Drug Repurposing for Triple-Negative and Inflammatory Breast Carcinoma with HDAC and HSP90 Inhibitors Combined with Niclosamide,” in Cancers by our Scientific Director Dr. Massimo Cristofanilli, with Pathology and Laboratory Medicine Drs. Udayan Bhattacharya, Mohammad Kamran and Dr. Marwa Manai on January 4th.
\“Urine-based multi-omic comparative analysis of COVID-19 and bacterial sepsis-induced ARDS,” in Molecular Medicine by EIPM Member Dr. Jan Krumsiek with Dr. Richa Batra on January 26th.
“Meta-hallmarks of aging and cancer,” in Cell Metabolism by our colleague Dr. Lorenzo Galluzzi on January 3rd.
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