Title | Control of host mitochondria by bacterial pathogens. |
Publication Type | Journal Article |
Year of Publication | 2022 |
Authors | Marchi S, Morroni G, Pinton P, Galluzzi L |
Journal | Trends Microbiol |
Volume | 30 |
Issue | 5 |
Pagination | 452-465 |
Date Published | 2022 May |
ISSN | 1878-4380 |
Keywords | Energy Metabolism, Homeostasis, Listeria monocytogenes, Mitochondria |
Abstract | Mitochondria control various processes that are integral to cellular and organismal homeostasis, including Ca fluxes, bioenergetic metabolism, and cell death. Perhaps not surprisingly, multiple pathogenic bacteria have evolved strategies to subvert mitochondrial functions in support of their survival and dissemination. Here, we discuss nonimmunological pathogenic mechanisms that converge on the ability of bacteria to control the mitochondrial compartment of host cells. |
DOI | 10.1016/j.tim.2021.09.010 |
Alternate Journal | Trends Microbiol |
PubMed ID | 34656395 |