Englander Institute for Precision Medicine

Publications

Found 695 results

Author Title Type [ Year

]

2019

Sivakumar R, Chan M, Shin JStella, Nishida-Aoki N, Kenerson HL, Elemento O, Beltran H, Yeung R, Gujral TS. 2019. Organotypic tumor slice cultures provide a versatile platform for immuno-oncology and drug discovery.. Oncoimmunology. 8(12):e1670019.

Liu B, Li L, Yang G, Geng C, Luo Y, Wu W, Manyam GC, Korentzelos D, Park S, Tang Z et al.. 2019. PARP Inhibition Suppresses GR-MYCN-CDK5-RB1-E2F1 Signaling and Neuroendocrine Differentiation in Castration-Resistant Prostate Cancer.. Clin Cancer Res. 25(22):6839-6851.

Beltran H, Oromendia C, Danila DC, Montgomery B, Hoimes C, Szmulewitz RZ, Vaishampayan U, Armstrong AJ, Stein M, Pinski J et al.. 2019. A Phase II Trial of the Aurora Kinase A Inhibitor Alisertib for Patients with Castration-resistant and Neuroendocrine Prostate Cancer: Efficacy and Biomarkers.. Clin Cancer Res. 25(1):43-51.

Malikic S, Mehrabadi FRashidi, Ciccolella S, Rahman MKhaledur, Ricketts C, Haghshenas E, Seidman D, Hach F, Hajirasouliha I, S Sahinalp C. 2019. PhISCS: a combinatorial approach for subperfect tumor phylogeny reconstruction via integrative use of single-cell and bulk sequencing data.. Genome Res. 29(11):1860-1877.

Jayaram A, Wingate A, Wetterskog D, Conteduca V, Khalaf D, Sharabiani MTaghavi Az, Calabrò F, Barwell L, Feyerabend S, Grande E et al.. 2019. Plasma Androgen Receptor Copy Number Status at Emergence of Metastatic Castration-Resistant Prostate Cancer: A Pooled Multicohort Analysis.. JCO Precis Oncol. 3

Prandi D, Demichelis F. 2019. Ploidy- and Purity-Adjusted Allele-Specific DNA Analysis Using CLONETv2.. Curr Protoc Bioinformatics. 67(1):e81.

Lue JK, Prabhu SA, Liu Y, Gonzalez Y, Verma A, Mundi PS, Abshiru N, Camarillo JM, Mehta S, Chen EI et al.. 2019. Precision Targeting with EZH2 and HDAC Inhibitors in Epigenetically Dysregulated Lymphomas.. Clin Cancer Res. 25(17):5271-5283.

Boehm KMichael, Bhinder B, Raja VJoseph, Dephoure N, Elemento O. 2019. Predicting peptide presentation by major histocompatibility complex class I: an improved machine learning approach to the immunopeptidome.. BMC Bioinformatics. 20(1):7.

Subbaramaiah K, Iyengar NM, Morrow M, Elemento O, Zhou XKathy, Dannenberg AJ. 2019. Prostaglandin E down-regulates sirtuin 1 (SIRT1), leading to elevated levels of aromatase, providing insights into the obesity-breast cancer connection.. J Biol Chem. 294(1):361-371.

Persi E, Prandi D, Wolf YI, Pozniak Y, Barnabas GD, Levanon K, Barshack I, Barbieri C, Gasperini P, Beltran H et al.. 2019. Proteomic and genomic signatures of repeat instability in cancer and adjacent normal tissues.. Proc Natl Acad Sci U S A. 116(34):16987-16996.

Armenia J, Wankowicz SAM, Liu D, Gao J, Kundra R, Reznik E, Chatila WK, Chakravarty D, G Han C, Coleman I et al.. 2019. Publisher Correction: The long tail of oncogenic drivers in prostate cancer.. Nat Genet. 51(7):1194.

Lhuillier C, Rudqvist N-P, Elemento O, Formenti SC, Demaria S. 2019. Radiation therapy and anti-tumor immunity: exposing immunogenic mutations to the immune system.. Genome Med. 11(1):40.

Fradet Y, Bellmunt J, Vaughn DJ, Lee JL, Fong L, Vogelzang NJ, Climent MA, Petrylak DP, Choueiri TK, Necchi A et al.. 2019. Randomized phase III KEYNOTE-045 trial of pembrolizumab versus paclitaxel, docetaxel, or vinflunine in recurrent advanced urothelial cancer: results of >2 years of follow-up.. Ann Oncol. 30(6):970-976.

Rodrigues DNava, Casiraghi N, Romanel A, Crespo M, Miranda S, Rescigno P, Figueiredo I, Riisnaes R, Carreira S, Sumanasuriya S et al.. 2019. RB1 Heterogeneity in Advanced Metastatic Castration-Resistant Prostate Cancer.. Clin Cancer Res. 25(2):687-697.

Roos-Weil D, Decaudin C, Armand M, Della-Valle V, Diop M'boybaK, Ghamlouch H, Ropars V, Hérate C, Lara D, Durot E et al.. 2019. A Recurrent Activating Missense Mutation in Waldenström Macroglobulinemia Affects the DNA Binding of the ETS Transcription Factor SPI1 and Enhances Proliferation.. Cancer Discov. 9(6):796-811.

Bancells C, Llorà-Batlle O, Poran A, Nötzel C, Rovira-Graells N, Elemento O, Kafsack BFC, Cortés A. 2019. Revisiting the initial steps of sexual development in the malaria parasite Plasmodium falciparum.. Nat Microbiol. 4(1):144-154.

Shoag JE, Wise DR, Sharaf RN, Sternberg CN. 2019. Somatic and germline sequencing in genitourinary oncology: genetics for the clinician.. Curr Opin Urol. 29(4):315-318.

Bhardwaj P, Ikeda T, Zhou XKathy, Wang H, Zheng XEmily, Giri DD, Elemento O, Verma A, Miyazawa M, Mukherjee S et al.. 2019. Supplemental estrogen and caloric restriction reduce obesity-induced periprostatic white adipose inflammation in mice.. Carcinogenesis. 40(7):914-923.

Hajirasouliha I, Tilgner HU. 2019. The tech for the next decade: promises and challenges in genome biology.. Genome Biol. 20(1):86.

Lan Y, Pan H, Li C, Banks KM, Sam J, Ding B, Elemento O, Goll MG, Evans T. 2019. TETs Regulate Proepicardial Cell Migration through Extracellular Matrix Organization during Zebrafish Cardiogenesis.. Cell Rep. 26(3):720-732.e4.

Locallo A, Prandi D, Fedrizzi T, Demichelis F. 2019. TPES: tumor purity estimation from SNVs.. Bioinformatics. 35(21):4433-4435.

Robinson BD, Vlachostergios PJ, Bhinder B, Liu W, Li K, Moss TJ, Bareja R, Park K, Tavassoli P, Cyrta J et al.. 2019. Upper tract urothelial carcinoma has a luminal-papillary T-cell depleted contexture and activated FGFR3 signaling.. Nat Commun. 10(1):2977.

Thirumavalavan N, J Gabrielsen S, Lamb DJ. 2019. Where are we going with gene screening for male infertility? Fertil Steril. 111(5):842-850.

2018

Halama A, Kulinski M, Dib SS, Zaghlool SB, Siveen KS, Iskandarani A, Zierer J, Prabhu KS, Satheesh NJ, Bhagwat AM et al.. 2018. Accelerated lipid catabolism and autophagy are cancer survival mechanisms under inhibited glutaminolysis.. Cancer Lett. 430:133-147.

Teater M, Dominguez PM, Redmond D, Chen Z, Ennishi D, Scott DW, Cimmino L, Ghione P, Chaudhuri J, Gascoyne RD et al.. 2018. AICDA drives epigenetic heterogeneity and accelerates germinal center-derived lymphomagenesis.. Nat Commun. 9(1):222.