Englander Institute for Precision Medicine

Publications

Found 229 results
Author Title Type [ Year(Asc)]
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2021
Elemento O, Leslie C, Lundin J, Tourassi G.  2021.  Artificial intelligence in cancer research, diagnosis and therapy.. Nat Rev Cancer. 21(12):747-752.
Cho BAngela, Iyengar NM, Zhou XKathy, Morrow M, Giri DD, Verma A, Elemento O, Pollak M, Dannenberg AJ.  2021.  Blood biomarkers reflect the effects of obesity and inflammation on the human breast transcriptome.. Carcinogenesis. 42(10):1281-1292.
Croker JA, Patel R, Campbell KS, Barton-Baxter M, Wallet S, Firestein GS, Kimberly RP, Elemento O.  2021.  Building biorepositories in the midst of a pandemic.. J Clin Transl Sci. 5(1):e92.
Bruno NE, Nwachukwu JC, Srinivasan S, Nettles CC, Izard T, Jin Z, Nowak J, Cameron MD, Boregowda SV, Phinney DG et al..  2021.  Chemical systems biology reveals mechanisms of glucocorticoid receptor signaling.. Nat Chem Biol. 17(3):307-316.
Rivas MA, Durmaz C, Kloetgen A, Chin CR, Chen Z, Bhinder B, Koren A, Viny AD, Scharer CD, Boss JM et al..  2021.  Cohesin Core Complex Gene Dosage Contributes to Germinal Center Derived Lymphoma Phenotypes and Outcomes.. Front Immunol. 12:688493.
Khosravi P, Lysandrou M, Eljalby M, Li Q, Kazemi E, Zisimopoulos P, Sigaras A, Brendel M, Barnes J, Ricketts C et al..  2021.  A Deep Learning Approach to Diagnostic Classification of Prostate Cancer Using Pathology-Radiology Fusion.. J Magn Reson Imaging. 54(2):462-471.
Xu Z, Verma A, Naveed U, Bakhoum SF, Khosravi P, Elemento O.  2021.  Deep learning predicts chromosomal instability from histopathology images.. iScience. 24(5):102394.
Cox N, Crozet L, Holtman IR, Loyher P-L, Lazarov T, White JB, Mass E, E Stanley R, Elemento O, Glass CK et al..  2021.  Diet-regulated production of PDGFcc by macrophages controls energy storage.. Science. 373(6550)
Pan H, Renaud L, Chaligne R, Bloehdorn J, Tausch E, Mertens D, Fink AMaria, Fischer K, Zhang C, Betel D et al..  2021.  Discovery of Candidate DNA Methylation Cancer Driver Genes.. Cancer Discov. 11(9):2266-2281.
McNally DR, Elemento O, Melnick A.  2021.  Dissecting bulk transcriptomes of diffuse large B cell lymphoma.. Cancer Cell. 39(10):1305-1307.
Montrose DC, Saha S, Foronda M, McNally EM, Chen J, Zhou XKathy, Ha T, Krumsiek J, Buyukozkan M, Verma A et al..  2021.  Exogenous and Endogenous Sources of Serine Contribute to Colon Cancer Metabolism, Growth, and Resistance to 5-Fluorouracil.. Cancer Res. 81(9):2275-2288.
Shohdy KS, Bareja R, Sigouros M, Wilkes DC, Dorsaint P, Manohar J, Bockelman D, Xiang JZ, Kim R, Ohara K et al..  2021.  Functional comparison of exome capture-based methods for transcriptomic profiling of formalin-fixed paraffin-embedded tumors.. NPJ Genom Med. 6(1):66.
Wolujewicz P, Aguiar-Pulido V, AbdelAleem A, Nair V, Thareja G, Suhre K, Shaw GM, Finnell RH, Elemento O, M Ross E.  2021.  Genome-wide investigation identifies a rare copy-number variant burden associated with human spina bifida.. Genet Med. 23(7):1211-1218.
Zoughbi WAl, Kim D, Alperstein SAnn, Ohara K, Manohar J, Greco N, Khani F, Robinson BD, Rao RA, Elemento O et al..  2021.  Incorporating cytologic adequacy assessment into precision oncology workflow using telepathology: An institutional experience.. Cancer Cytopathol. 129(11):874-883.
Beg S, Bareja R, Ohara K, Eng KWha, Wilkes DC, Pisapia DJ, Zoughbi WAl, Kudman S, Zhang W, Rao R et al..  2021.  Integration of whole-exome and anchored PCR-based next generation sequencing significantly increases detection of actionable alterations in precision oncology.. Transl Oncol. 14(1):100944.
Marderstein AR, Davenport ER, Kulm S, Van Hout CV, Elemento O, Clark AG.  2021.  Leveraging phenotypic variability to identify genetic interactions in human phenotypes.. Am J Hum Genet. 108(1):49-67.
Kaya C, Dorsaint P, Mercurio S, Campbell AM, Eng KWha, Nikiforova MN, Elemento O, Nikiforov YE, Sboner A.  2021.  Limitations of Detecting Genetic Variants from the RNA Sequencing Data in Tissue and Fine-Needle Aspiration Samples.. Thyroid. 31(4):589-595.
Rendeiro AF, Vorkas CKyriakos, Krumsiek J, Singh HK, Kapadia SN, Cappelli LVincenzo, Cacciapuoti MTeresa, Inghirami G, Elemento O, Salvatore M.  2021.  Metabolic and Immune Markers for Precise Monitoring of COVID-19 Severity and Treatment.. Front Immunol. 12:809937.
Li J, Duran MA, Dhanota N, Chatila WK, Bettigole SE, Kwon J, Sriram RK, Humphries MP, Salto-Tellez M, James JA et al..  2021.  Metastasis and Immune Evasion from Extracellular cGAMP Hydrolysis.. Cancer Discov. 11(5):1212-1227.
Melms JC, Biermann J, Huang H, Wang Y, Nair A, Tagore S, Katsyv I, Rendeiro AF, Amin ADipak, Schapiro D et al..  2021.  A molecular single-cell lung atlas of lethal COVID-19.. Nature. 595(7865):114-119.
Bloehdorn J, Braun A, Taylor-Weiner A, Jebaraj BMichael Ch, Robrecht S, Krzykalla J, Pan H, Giza A, Akylzhanova G, Holzmann K et al..  2021.  Multi-platform profiling characterizes molecular subgroups and resistance networks in chronic lymphocytic leukemia.. Nat Commun. 12(1):5395.
Nilsson-Payant BE, Uhl S, Grimont A, Doane AS, Cohen P, Patel RS, Higgins CA, Acklin JA, Bram Y, Chandar V et al..  2021.  The NF-κB Transcriptional Footprint Is Essential for SARS-CoV-2 Replication.. J Virol. 95(23):e0125721.
Doane AS, Chu C-S, Di Giammartino DCampigli, Rivas MA, Hellmuth JC, Jiang Y, Yusufova N, Alonso A, Roeder RG, Apostolou E et al..  2021.  OCT2 pre-positioning facilitates cell fate transition and chromatin architecture changes in humoral immunity.. Nat Immunol. 22(10):1327-1340.
Shah Y, Verma A, Marderstein AR, White J, Bhinder B, J Medina SGarcia, Elemento O.  2021.  Pan-cancer analysis reveals molecular patterns associated with age.. Cell Rep. 37(10):110100.
Marderstein AR, Kulm S, Peng C, Tamimi R, Clark AG, Elemento O.  2021.  A polygenic-score-based approach for identification of gene-drug interactions stratifying breast cancer risk.. Am J Hum Genet. 108(9):1752-1764.