Englander Institute for Precision Medicine

Publications

Found 692 results
Author Title [ Type(Desc)] Year
Journal Article
Smith MR, Hussain M, Saad F, Fizazi K, Sternberg CN, E Crawford D, Kopyltsov E, Park CH, Alekseev B, Montesa-Pino Á et al..  2022.  Darolutamide and Survival in Metastatic, Hormone-Sensitive Prostate Cancer.. N Engl J Med. 386(12):1132-1142.
Hussain M, Tombal B, Saad F, Fizazi K, Sternberg CN, E Crawford D, Shore N, Kopyltsov E, Kalebasty ARezazadeh, Bögemann M et al..  2023.  Darolutamide Plus Androgen-Deprivation Therapy and Docetaxel in Metastatic Hormone-Sensitive Prostate Cancer by Disease Volume and Risk Subgroups in the Phase III ARASENS Trial.. J Clin Oncol. 41(20):3595-3607.
Assaad MAl, Shin N, Sigouros M, Manohar J, Antysheva Z, Kotlov N, Kiriy D, Nikitina A, Kleimenov M, Tsareva A et al..  2023.  Deciphering the origin and therapeutic targets of cancer of unknown primary: a case report that illustrates the power of integrative whole-exome and transcriptome sequencing analysis.. Front Oncol. 13:1274163.
Oudard S, Benhamouda N, Escudier B, Ravel P, Tran T, Levionnois E, Negrier S, Barthelemy P, Berdah JFrançois, Gross-Goupil M et al..  2021.  Decrease of Pro-Angiogenic Monocytes Predicts Clinical Response to Anti-Angiogenic Treatment in Patients with Metastatic Renal Cell Carcinoma.. Cells. 11(1)
Khosravi P, Kazemi E, Imielinski M, Elemento O, Hajirasouliha I.  2018.  Deep Convolutional Neural Networks Enable Discrimination of Heterogeneous Digital Pathology Images.. EBioMedicine. 27:317-328.
Khosravi P, Lysandrou M, Eljalby M, Li Q, Kazemi E, Zisimopoulos P, Sigaras A, Brendel M, Barnes J, Ricketts C et al..  2021.  A Deep Learning Approach to Diagnostic Classification of Prostate Cancer Using Pathology-Radiology Fusion.. J Magn Reson Imaging. 54(2):462-471.
Khosravi P, Kazemi E, Zhan Q, Malmsten JE, Toschi M, Zisimopoulos P, Sigaras A, Lavery S, Cooper LAD, Hickman C et al..  2019.  Deep learning enables robust assessment and selection of human blastocysts after in vitro fertilization.. NPJ Digit Med. 2:21.
Yao P, Witte D, German A, Periyakoil P, Kim YEun, Gimonet H, Sulica L, Born H, Elemento O, Barnes J et al..  2023.  A deep learning pipeline for automated classification of vocal fold polyps in flexible laryngoscopy.. Eur Arch Otorhinolaryngol.
Xu Z, Verma A, Naveed U, Bakhoum SF, Khosravi P, Elemento O.  2021.  Deep learning predicts chromosomal instability from histopathology images.. iScience. 24(5):102394.
Courtiol P, Maussion C, Moarii M, Pronier E, Pilcer S, Sefta M, Manceron P, Toldo S, Zaslavskiy M, Le Stang N et al..  2019.  Deep learning-based classification of mesothelioma improves prediction of patient outcome.. Nat Med. 25(10):1519-1525.
Trieu T, Martinez-Fundichely A, Khurana E.  2020.  DeepMILO: a deep learning approach to predict the impact of non-coding sequence variants on 3D chromatin structure.. Genome Biol. 21(1):79.
Puca L, Gavyert K, Sailer V, Conteduca V, Dardenne E, Sigouros M, Isse K, Kearney M, Vosoughi A, Fernandez L et al..  2019.  Delta-like protein 3 expression and therapeutic targeting in neuroendocrine prostate cancer.. Sci Transl Med. 11(484)
Marderstein AR, Uppal M, Verma A, Bhinder B, Tayyebi Z, Mezey J, Clark AG, Elemento O.  2020.  Demographic and genetic factors influence the abundance of infiltrating immune cells in human tissues.. Nat Commun. 11(1):2213.
Cibula D, Rob L, Mallmann P, Knapp P, Klat J, Chovanec J, Minar L, Melichar B, Hein A, Kieszko D et al..  2021.  Dendritic cell-based immunotherapy (DCVAC/OvCa) combined with second-line chemotherapy in platinum-sensitive ovarian cancer (SOV02): A randomized, open-label, phase 2 trial.. Gynecol Oncol. 162(3):652-660.
Darabedian N, Ji W, Fan M, Lin S, Seo H-S, Vinogradova EV, Yaron TM, Mills EL, Xiao H, Senkane K et al..  2023.  Depletion of creatine phosphagen energetics with a covalent creatine kinase inhibitor.. Nat Chem Biol. 19(7):815-824.
Jordan ERose, Jahreiss L, Kasi PMurtaza.  2021.  Deploying an artificial intelligence-based online search tool to increase patients' access to and understanding of solid tumor gastrointestinal clinical trials.. J Gastrointest Oncol. 12(5):2045-2051.
Berchuck JE, Baca SC, McClure HM, Korthauer K, Tsai HK, Nuzzo PVitale, Kelleher KM, He M, Steinharter JA, Zacharia S et al..  2022.  Detecting Neuroendocrine Prostate Cancer Through Tissue-Informed Cell-Free DNA Methylation Analysis.. Clin Cancer Res. 28(5):928-938.
Fucikova J, Kepp O, Kasikova L, Petroni G, Yamazaki T, Liu P, Zhao L, Spisek R, Kroemer G, Galluzzi L.  2020.  Detection of immunogenic cell death and its relevance for cancer therapy.. Cell Death Dis. 11(11):1013.
Rennert H, Eng K, Zhang T, Tan A, Xiang J, Romanel A, Kim R, Tam W, Liu Y-C, Bhinder B et al..  2016.  Development and validation of a whole-exome sequencing test for simultaneous detection of point mutations, indels and copy-number alterations for precision cancer care.. NPJ Genom Med. 1:16019-.
Baggiolini A, Callahan SJ, Montal E, Weiss JM, Trieu T, Tagore MM, Tischfield SE, Walsh RM, Suresh S, Fan Y et al..  2021.  Developmental chromatin programs determine oncogenic competence in melanoma.. Science. 373(6559):eabc1048.
Cox N, Crozet L, Holtman IR, Loyher P-L, Lazarov T, White JB, Mass E, E Stanley R, Elemento O, Glass CK et al..  2021.  Diet-regulated production of PDGFcc by macrophages controls energy storage.. Science. 373(6550)
Taza F, Holler AE, Fu W, Wang H, Adra N, Albany C, Ashkar R, Cheng HH, Sokolova AO, Agarwal N et al..  2021.  Differential Activity of PARP Inhibitors in - Versus -Altered Metastatic Castration-Resistant Prostate Cancer.. JCO Precis Oncol. 5
McNair C, Xu K, Mandigo AC, Benelli M, Leiby B, Rodrigues D, Lindberg J, Gronberg H, Crespo M, De Laere B et al..  2018.  Differential impact of RB status on E2F1 reprogramming in human cancer.. J Clin Invest. 128(1):341-358.
Wittenbecher C, Cuadrat R, Johnston L, Eichelmann F, Jäger S, Kuxhaus O, Prada M, F M DGreco, Hicks AA, Hoffman P et al..  2022.  Dihydroceramide- and ceramide-profiling provides insights into human cardiometabolic disease etiology.. Nat Commun. 13(1):936.
Hertel J, Rotter M, Frenzel S, Zacharias HU, Krumsiek J, Rathkolb B, de Angelis MHrabe, Rabstein S, Pallapies D, Brüning T et al..  2018.  Dilution correction for dynamically influenced urinary analyte data.. Anal Chim Acta. 1032:18-31.